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Patient and Survivor Resources

You are not alone

and not to blame.

Preeclampsia is not your fault. It is a complex disease that does not discriminate and affects many pregnant women around the world.

Olympic athlete and Comanche Board of Directors member Allyson Felix shares her preeclampsia story

Our commitment to preeclampsia survivors

We are committed to prioritizing patient needs and integrating the patient experience into every facet of our business in our pursuit to develop a treatment for preeclampsia. We understand that being diagnosed with preeclampsia can be overwhelming, and there is often a lack of information about the condition and its warning signs. We are fully committed to enhancing the lives of individuals affected by preeclampsia and are working tirelessly to develop innovative solutions that lead to improved health outcomes.

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What is Preeclampsia?

Many women have never heard of preeclampsia and are understandably frightened when they receive such a diagnosis. The disease is often first apparent during a routine prenatal visit in the third trimester of pregnancy. A common clinical sign of preeclampsia is elevated maternal blood pressure, though other clinical signs and symptoms may include protein in the urine (a sign of kidney damage), headache, visual disturbances, abdominal pain, or swelling of the arms and legs. Preeclampsia has historically been a challenge to diagnose accurately because pregnant women experience a wide and varied spectrum of symptoms. Some pregnant women with preeclampsia may feel completely normal. Currently, the only “cure” for preeclampsia is delivery of the baby and placenta, most often prematurely, but this does not resolve the lasting physical and mental harm done by the disease.
Preeclampsia afflicts more than 10 million women every year around the world with devastating short and long term consequences to both mother and baby. Tragically, it accounts for nearly 80,000 maternal and over 500,000 fetal deaths each year. Although all pregnant women are at risk of developing the disease, it disproportionately affects women of color, women in their teens or over forty years of age, women who have undergone in vitro fertilization, and those in lower socio-economic status.
The burden of preeclampsia is accelerating worldwide and remains an urgent unmet medical need despite more than 50 years of research seeking a cure. It is now a public health crisis.
We are leading a global effort to end this disease and improve maternal health by conducting high quality, safe clinical trials in this complex patient population.
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Resources

We have compiled informative websites, a support group, and other resources to help you stay informed and connected about this serious pregnancy complication.

We are proud supporters of Preeclampsia Foundation and EndPreeclampsia:

Preeclampsia Foundation

Preeclampsia.org

A non-profit organization that raises awareness and funds research for preeclampsia and other hypertensive disorders of pregnancy.

EndPreeclampsia

EndPreeclampsia.org

A patient advocacy organization that aims to increase awareness, education, and research about preeclampsia in order to improve the lives of women and babies affected by the condition.

Additional Educational or Patient Support Resources:

Preeclampsia, Eclampsia & HELLP Syndrome Survivors Global Support Network

facebook.com/groups/preeclampsia/

A Global, evidence-based, Support, Awareness, Education and Advocacy group for those who have been affected by Preeclampsia, Eclampsia, HELLP Syndrome, Gestational Hypertension, Chronic hypertension or any hypertensive disorder of pregnancy.

American College of Obstetricians and Gynecologists

acog.org/womens-health/faqs/preeclampsia-and-high-blood-pressure-during-pregnancy

A professional medical association that provides evidence-based guidelines and resources for obstetricians and gynecologists, including information on preeclampsia and high blood pressure during pregnancy.

Society for Maternal-Fetal Medicine

highriskpregnancyinfo.org

A professional medical association that provides resources and education to improve pregnancy outcomes, including information and frequently asked questions about preeclampsia.

Up to Date

uptodate.com/contents/preeclampsia-beyond-the-basics

An evidence-based clinical resource. It includes a collection of medical and patient information.

Contact Us

50 Beharrell St, Unit B
Concord, MA 01742

Contact Us

Comanche is a biopharmaceutical company developing an investigational siRNA medicine for preterm preeclampsia. We envision a world where all women and their babies have access to safe and effective therapies for treating life threatening complications of pregnancy, and those solutions must be evidence-based and affordable.

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